Tubulin α (Acetyl Lys112) Polyclonal Antibody
簡要描述：Tubulin α (Acetyl Lys112) Polyclonal Antibody宿主: Polyclonal, Rabbit,IgG反應性: Human;Mouse;Rat應用: WB;ELISA
產品型號： YP-Ab-02904
所屬分類：標簽內參抗體
更新時間：2024-11-01
詳細說明：
Tubulin α (Acetyl Lys112) Polyclonal Antibody
抗體，也叫免疫球蛋白（Ig），是一種能特異性結合抗原的糖蛋白，而抗原是在易感染動物體內引發(fā)抗體產生的物質。在體內，抗體是由于外源性分子的侵襲而產生的。抗體以一個或者多個Y字形單體存在，每個Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據它們的分子量大小來命名的。Y字形結構的頂端是可變區(qū)，為抗原結合部位。任何一個抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結構上的差異），每一個抗體的重鏈則決定了它的類或型。
產品詳情
Acetyl-Tubulin α (K112) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K112.
免疫原詳細信息
Synthesized acetyl-peptide derived from human Tubulin α around the acetylation site of K112.
相關試劑
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
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備注：圖片僅供參考。僅供科研，不可用于臨床。
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